Clinical Variants of Guillain Barre Syndrome!
During last few decades, numerous variants of Guillain Barre Syndrome are documented. These illness variants share similar patterns of symptom, development, recovery, overlap, and possible immune treatments. Presently there are six identified variants of Guillain Barre Syndrome.
1- Acute inflammatory demyelinating polyneuropathy or AIDP
Generally ADIP is more common type of Guillain Barre Syndrome. At the moment, there are many identified variants of Guillain Barre Syndrome, although majority of medical professionals consider AIDP as Guillain Barre Syndrome. Infrastructure and economical advancement of any country plays a vital rule in the ratio of people who suffer from Guillain Barre Syndrome, for example 1 case of GBS is reported in population of 25,000-170,000. The most common type of GBS variant affects people in old age, however this cruel disease is not limited to just old people, children and adults, male and female everyone gets same symptoms and similar severe complications.
2-Miller Fisher Syndrome
Miller Fisher Syndrome is another common clinical variant of Guillain Barre Syndrome, it’s identified in approximately in 5% of all Guillain Barre Syndrome cases. This syndrome include of areflexia, ataxia, and ophthalmoplegia. Initially it is noted between trunk and in the gait, it’s mainly involves lower limb. It speedily spread all over in the body damaging entire peripheral nerves. The average course of recovery may be different in various patients, few patients show fast recovery while others may suffer chronic symptoms of Guillain Barre Syndrome. There is a close connection between antiganglioside antibodies and the Miller Fisher Syndrome.
3- AMAN Variant
The AMAN variant is well connected with high titers of antibodies to gangliosides and enteric C jejuni infections. Patients with AMAN syndrome demonstrate similar signs as clinically appear in patients suffering with the demyelinating type of Guillain Barre Syndrome. AMAN is diagnosed by electrodiagnostic study results that are steady by speedy axonopathy.
4- Wallerianlike Degeneration
Wallerianlike Degeneration is another significant variant shown in Biopsies without lymphocyte inflammation. Several cases have been identified in rural areas of China, particularly in young adults and children in the summer months. Axonal cases may happen commonly outside of North America and Europe. There are also noticeable differences between AMAN from cases of axonal Guillain Barre Syndrome reported in the West. Frequently the Prognosis is rather productive, though time of complete recovery may be different in many patients. Some patients recover fast and show amazing recovery in few months while others may have to experience the painful complications even years of first attack